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This work was supported by the Ministry of Science and Technology of China (nos

Updated January 15, 2025

The variability in clinical response among patients with BD has been increasingly attributed to genetic factors, with specific polymorphisms in genes such as GSK3B, NTRK2, ADCY1, FAM177A1, GRAMD1B, and ZNF804A showing strong associations with treatment outcomes
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But the first few days after the injury are also when BDNF is needed the most for healing

The Delphi method was used to determine experts consensus on the open questions [17]