glutathione biosynthesis bacteria pathway and glutathione-ascorbate cycle For Glutathione synthetase - Wikipedia
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2024;9:61 Tzavlaki K, Moustakas A
M., Plou, F

One major way the body defends itself against oxidative stress is through antioxidant enzymes such as catalase, superoxide dismutase (SOD), and glutathione peroxidase (GPx)

Deficiency may lead to brittle nails, hair loss, or dry, damaged skin
Correlated with the MAPK pathway, calycosin was able to abolish RANKL-induced osteoclast formation from primary bone marrow macrophages [62]

Some potential refinements of the model would be to include these aspects
