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Reactive thrombocytosis occurs secondary to the release of cytokines after an inciting infectious or inflammatory event, and the role of platelets and platelet-derived mediators in stimulating inflammation has been described at the molecular level

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The decision to continue, adjust, or discontinue therapy should be based on objective body composition measurements (DEXA scans, circumference measurements), achievement of fat loss goals, tolerance and side effect profile, and physician assessment of metabolic markers

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