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2.2 SLC7A11 and the mechanism of glioma development Ferroptosis is an important form of programmed cell death that occurs in gliomas, the intracellular antioxidant system often fails to eliminate excessive ROS generated by iron ion-induced Fenton reactions and lipid peroxidation
Other effects of coenzyme Q 10 on blood lipids have not been reported (51, 53, 54)

It is our hypothesis that in the setting of COVID-19 and oxidative stress, patients with comorbidities may have compromised levels of GS and GCL, the enzymes involved in GSH synthesis For this reason, we suggest directly supplementing liposomal glutathione, instead of NAC as patients with deficient levels of GS and GCL will not be able to use NAC as substrate for GSH synthesis
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10.3390/ijms21072440 220

Bringhen S, Pour L, Vorobyev V, et al