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Details of producing such pharmaceutical compositions comprising targeted (PEG) liposomes are described in US Patent No.6, 372,250

Therefore, a deeper understanding of IRI pathophysiology, while addressing knowledge gaps on the complex and interconnected aspects of IRI such as mitochondrial dysfunction, calcium loading, oxidative stress and inflammatory response in pre-clinical models and patients, is essential to guide future therapeutic approaches

Its core purpose is to move beyond symptom management, aiming to repair, replace, or regenerate cells and tissues that have been damaged by disease, trauma, or natural aging

[DOI] [PMC free article] [PubMed] [Google Scholar] 118.Sever A.Z., Sever M., Vidovic T., Lojo N., Kolenc D., Vuletic L.B., Drmic D., Kokot A., Zoricic I., Coric M., et al