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The metabolic syndrome is associated with elevated circulating C-reactive protein in healthy reference range, a systemic low-grade inflammatory state

Guo P, Liu L, Yang X, Li M, Zhao Q, Wu H

A recent study analyzed the circulating microbiome of patients with alcoholic hepatitis, and found a decrease in Bacteroidetes and an enrichment of Fusobacteria

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For systemic peptides like MOTS-c or SS-31 , the injection site matters less because the peptide enters systemic circulation regardless of where it is administered