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Description
Reducing agents NADH and FADH 2 that are generated from glycolysis and the tricarboxylic acid cycle transport electrons to complexes I (NADH, ubiquinone oxidoreductase) and II (succinate dehydrogenase) [25,26]
Behav Brain Res 256:564574
This oxidative stress disrupts mitochondrial regulation and activates vital inflammatory signaling pathways, such as NF-B and JAK/STAT
In dieren ligt CYP2E1-inductie ten grondslag aan de interactie tussen chronisch ethanolgebruik en PCM hepatotoxiciteit [22]
Cells become abnormally and inefficiently dependent on aerobic glycolysis (the Warburg effect), which cannot sustain long-term survival, ultimately promoting activation-induced apoptosis and the collapse of the CD4+ T cell pool (54, 55)
116 KinnartI.MandersL.HeyninckT.ImberechtsD.PraschbergerR.SchoovaertsN.et al (2024)
