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Transcriptomic analyses have attempted to classify GB into subtypes that could predict treatment response 1,2,3 , and a recent study that used a pathway-based classification defined metabolism-associated subtypes with distinct therapeutic vulnerabilities

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For H&E staining sections were processed following standard laboratory procedures

Despite the limited diagnostic capabilities of many current biomarkers, future research should aim to enhance diagnostic accuracy and efficiency through the integration of technologies such as artificial intelligence and machine learning

Diagnostics 13 , 206 (2023)