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According to researchers who conducted a clinical study on Protandim, each of these ingredients has been reported to increase levels of antioxidant activity in the body, but a low dose of each was chosen to avoid unwanted pharmacological effects (Nelson, Free Radic Biol Med 2006)

Interactions with Other Supplements Vitamin C: Synergistic vitamin C spares glutathione and helps regenerate it from GSSG

[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Nii-Kono T., Iwasaki Y., Uchida M., Fujieda A., Hosokawa A., Motojima M., Yamato H., Kurokawa K., Fukagawa M

Rosenbloom MH, Kashyap B, DiazOchoa A, et al

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High positive contributions from enzymes like 6-phosphogluconate dehydrogenase (6GPD: 0.333), glutathione S-transferase (GST: 0.322), and metabolites like sucrose (0.317) suggest that this axis reflects the oxidative and metabolic responses under stress