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Asthenic astrocytes may be linked to a hyperactive glutamatergic transmission (due to the reduced glutamate clearance observed in bipolar disorder 295,296 , reduced neuroprotection and metabolic abnormalities 297

Michele Ross is a freelance writer based in Los Angeles

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* Correspondence: Yanru Li, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers