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The recognition of risk factors is of critical importance in the timely identification of subclinical/early DPN for effective disease control and prevention of hazards (i.e., ulcer, gangrene, and amputation) and social burden ( Table 1 Risk factors of DPN ( HbA1c, glycated hemoglobin

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(2009) reviewed glutathiones role as the master intracellular antioxidant, describing its enzymatic recycling, compartmentalization, and signaling functions

3MST and R196G also decreased the GSH level in the presence of 3MP, while C247S and R187G did not (Fig

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