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In addition to transcriptional regulators, N
Studies have shown that knocking down the NNMT gene leads to increased expenditure of energy in adipocytes (Xu et al., 2022)

While melt shift analysis helps identify proteins with biophysical changes, TPCA is a method that more specifically monitors binary protein interactions and protein complex dynamics (75)
(PubMed) Lenzi A, Lombardo F, Sgro P, et al

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