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Transposable elements are repetitive regions of the genome that are silenced and usually display high levels of DNA methylation
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Design, Setting, Participants This is a phase II, randomized, multi-center, double-blind, placebo-controlled trial among 60 participants with mild cognitive impairment or dementia due to AD
In this Review, the authors describe perturbations in neuroimmune, metabolic and oxidative pathways in major depressive disorder and explore how imbalances in each of these pathways can contribute to the acute phase of the disease.
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