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Kawaguchi M, Kataoka H

Symptoms may get worse with sitting, standing, sleeping, walking or climbing stairs

While considered reliable and straightforward, most of the experimental assays are labor intensive and are impractical to implement with a large number of mAb candidates

TB-500 (Thymosin Beta-4 fragment) is involved in actin regulation and cellular migration pathways

NBs originate from neural crest cells and typically form in the abdominal or thoracic regions in paraspinal ganglia ( MYCN is a transcription factor belonging to the highly homologous MYC -family of cellular oncogenes, ubiquitously expressed in mammals

Abbreviations Ctrl: Control EASE: Expression analysis systematic explorer FDR: False discovery rate GSH: Glutathione GSSG: Glutathione disulfide KO: Knockout MAPK: Mitogen-activated protein kinase MT: Metallothionein PCA: Principal component analysis PHH: Primary human hepatocytes RLU: Relative light units ROS: Reactive oxygen species WD: Wilsons disease References Sandahl TD, Laursen TL, Munk DE, Vilstrup H, Weiss KH, Ott P (2020) The prevalence of wilsons disease: an update