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Description
This approach has many inherent advantages, and represents the method of choice, particularly if it can be used for the early diagnosis of renal lesions or dysfunction in experimental animals being used for nephrotoxicity screening studies

Cell culture The following cell lines were used in this study: IMR90 and WI-38 human fetal lung fibroblasts (female), BJ human foreskin fibroblasts (male), NIH3T3 mouse fibroblasts, wt and bax/bak / littermate Baby Mouse Kidney (BMK) cells, Human Embryonic Kidney (HEK) 293LTV

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