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Given its pivotal role in inflammation, oxidative stress, and ferroptosis, ROS represents a focal node for investigating the (nuclear factor E2-related factor 2) Nrf2 pathway and ferroptosis, both of which are intricately linked to ROS

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Early-stage ferroptotic tumor cells release HMGB1, ATP, and calreticulin, which drive dendritic cell (DC) maturation and antigen presentation, promoting robust CD8 T-cell priming and infiltration [106,107,108,109]