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Methylmalonic acid and homocysteine levels provide accurate diagnosis when serum B12 falls between 200-400 picograms per milliliter (the gray zone where symptoms appear but standard tests show normal results)

The SmPC lists fatigue as a common side effect, while nausea, vomiting, and diarrhoea are very common side effects (affecting more than 1 in 10 people)

While this is an effective method, it hasnt been carefully studied in clinical trials (22)

This is also the highest dose that was studied in the SURPASS and SURMOUNT trials

A cross-sectional study of 700 community-living, physically disabled women over the age of 65 found that vitamin B 12 -deficient women were twice as likely to be severely depressed as non-deficient women (97)

These syringes are marked in units where 1 mL = 100 IU (International Units) by convention