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Finally, the increased (the present ischemia/reperfusion study) or decreased (inferior caval vein occlusion study) (Vukojevic et al., 2018) expression of Vegfr2 that coincides with continuously increased Nos3 expression may reflect particularities of the organization of the response in the hippocampus after bilateral carotid artery ligation during reperfusion and ischemia in rats with occluded inferior caval veins (Vukojevic et al., 2018)

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Furthermore, extracellular lactate must enter cells through MCTs before contributing to lactylation reactions, which have been demonstrated to modulate ferroptosis through multiple mechanisms (51)