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Within the nucleus, NRF2 binds to promoter regions of target genes which contain antioxidant response element (ARE) sequences, ultimately inducing the transcription of cytoprotective genes, i.e., those encoding for phase II detoxification enzymes and antioxidants

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Update 25 (2), 202223

Myosin light chain phosphatase is a downstream target of Rho-kinase in endothelin-1-induced transactivation of the TGF- receptor

Beads were washed once with lysis buffer (without benzonase) and 4 times in TBS

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Sharma S., Dixon T., Jung S., Graff E.C., Forney L.A., Gettys T.W., Wanders D