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If pure water is introduced directly into the bloodstream without adding solutes to make it isotonic, water will rapidly rush into the red blood cells via osmosis, causing them to swell and burst (hemolysis)

Nabah et al., 2005)

Many patients use one or both methods depending on their goals

This is due to the high frequency at which functional and morphological changes within this region have been identified in studies of negative affect, and the function of this region as a point of integration between visceral, attentional and affective information important for homeostasis and allostasis

Role of the normal gut microbiota