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On the contrary, SerpinB2 depletion in macrophages kindled pro-inflammatory cytokine production with concomitant high oxidative phosphorylation and apoptosis of VAT resident macrophages, indicating the role of SerpinB2 in controlling exaggerated mitochondrial respiration, inflammation, and VAT resident macrophage survival in obesity

781 Additionally, hepatocytes near the injury site upregulate Wnt/-catenin target genes and pericentral metabolic enzymes regulated by Wnt/-catenin, consistent with the regenerative effects promoted by Wnt2 and Wnt9b in pericentral endothelial cells

Nayan Patel [00:48:16]: Right

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