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Supplemental arginine may attenuate nitrate tolerance but can amplify acute hypotension

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A single-center prospective study on 66 patients

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The copper complexes of the peptides Gly-Gly-His (GGH), Gly-His-Lys (GHK) reduced TNF-alpha induced secretion of proinflammatory cytokine IL-6, in normal human dermal fibroblasts, while saccharomyces/copper ferment (OligolidesA Copper) had no effect