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Dysfunctional hypothalamic function can be seen in ME/CFS patients in the form of up-regulation of hypothalamic 5-hydroxytryptamine (5-HT) receptors (441) and abnormal arginine/vasopressin responses to deprivation tests and water loading (440)

Nitrogen gas is also introduced in containers before and after filling to avoid oxidation and contamination
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Figure 4F illustrates that both targeting peptides significantly inhibited caspase-3 activity since decreasing fluorescence intensities of caspase-3 substrates were observed
