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3.7 Loperamide Loperamide, an inexpensive, over-the-counter, mu-opioid receptor agonist, is commonly used as an antidiarrheal agent
Thus, various tumors, including glioma, secondary glioblastoma, and acute myeloid leukemia (AML), harboring heterozygous point mutations in the active sites of IDH1/2 show dramatic increases in the R-2-HG levels 111,113,114,115

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[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Carmella S.G., Chen M., Zhang Y., Zhang S., Hatsukami D.K., Hecht S.S

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