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This complex can then be cleared by MRPs ( Moreover, Pt (IV) complexes have been intensively exploited in the development of GSH-responsive platinum drugs for controlled intracellular drug release

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Additionally, in the context of lowered ATP production, which is a hallmark of mitochondrial diseases, it is important to note that NAC, essentially only being a form of cysteine, will require 2 ATP molecules to be converted to glutathione

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What are reactive oxygen species, free radicals, and oxidative stress in skin diseases

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doi: 10.3390/antiox11020413

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Foyer and Noctor 2011

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