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Snyder EE, Walts B, Prusse L, Chagnon YC, Weisnagel SJ, Rankinen T, et al

Recently, growing evidence supports the concept that AD is a metabolic disease of type 3 diabetes mellitus, based on the fact that insulin resistance and dysfunctional glucose metabolism in the brain are often found in patients with AD and that A deposition induces reduced expression of insulin receptor on neuronal cells (

Immunometabolism and immune response regulate macrophage function in atherosclerosis

(2021) 118:e2110610118

As described above, the endothelium produces and activates molecules and inflammatory factors, which exit the bloodstream and reach the target tissue through the endothelium

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