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High ChoK expression correlates with early-stage non-small-cell lung cancer (NSCLC) patients at risk of recurrence, whereas lower expression identifies patients with favorable outcomes, potentially allowing for less aggressive treatment approaches (215)
When PAD progresses to the advanced disease stage, the ischemic injury becomes more severe, manifesting as rest pain, chronic ulceration, gangrene, and finally loss of tissue
However, there is no clear understanding of the exact mechanism of action of reductive stress on male reproduction, and further research is required
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