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Colloid goiter is a definite pathologic entity, as described in Chapter 17

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As a part of the counteraction of the severe vessel and multiorgan failure syndrome, counteracted were the brain, lung, liver, kidney, gastrointestinal lesions, and in particular, the counteraction of the heart arrhythmias and infarction

However, some patients report sleep disturbances that may be indirectly related to gastrointestinal symptoms or metabolic changes during treatment

Persistent vomiting, inability to tolerate oral intake, or signs of bowel obstruction require immediate evaluation