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Changes in expression and distribution of claudin-2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohns disease

GHK was administered intraperitoneally at doses of 2.6, 26, and 260 g/ml/day every other day from the 4th to the 21st day after BLM instillation

Gastrointestinal repair pathway research

87 -89 These self-assembled peptides undergo gelation through noncovalent self-assembly mechanisms, enabling the incorporation of bioactive groups that replicate protein functions

Tirzepatide offers similar benefits through a dual-action mechanism (Mounjaro, Zepbound)
