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Ghrelin, a gastric peptide with potent GH secretagogue properties, amplifies hypothalamic GHRH secretion and synergizes its pituitary GH-stimulation effects ( Insulin Insulin suppresses GH secretion, but the underlying mechanisms are not well-understood, and are postulated to occur at several different levels

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The search was restricted to English-language papers and included grey literature

Study Highlights The study revealed that Petrelintide, at a specific dose, achieved a placebo-adjusted weight loss of 6.9% over 16 weeks

If you are currently taking medicines with a narrow therapeutic index, your prescriber may recommend closer monitoring during the initiation and dose escalation phases