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In addition to the Wnt pathway, toxins impact the Hippo pathway, essential for tissue homeostasis and regeneration

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10.1016/j.celrep.2014.12.036

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5), showing the extensive degeneration of hepato- cytes with necrosis, inflammation, vacuolization, inflammatory cell in- filtration and fatty degenerative changes (panel C), as compared with control (panel A)