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About this article Cite this article de Oliveira, D.C., da Silva Lima, F., Sartori, T
The abnormal expression of GPx2 was detected in different tumors, and GPx2 was up-regulated in colorectal cancer [51, 52] and down-regulated in prostate intraepithelial neoplasia [53], suggesting that GPx2 plays complex roles in tumorigenesis [23]
10.1016/j.metabol.2017.11.019 Metabolism 11 BrysM.FoxM.AgarwalS.BiagioniM.DacpanoG.KumarP.et al (2016)
Thus, oxidative stress can cause disruptions in normal mechanisms of cellular signaling
They monitored IGF-1 levels, tracked insulin sensitivity, and conducted oral glucose tolerance tests
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