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As shown in Table 1 and Figure 6, in the pursuit of structurally diverse NNMT inhibitors, researchers have identified certain macrocyclic peptides that bind to NNMT, displaying potent inhibition with Half-maximal inhibitory concentration (IC 50 ) values as low as 229 nM (Van Haren et al., 2021)

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Understanding who responds best and who should avoid it prevents wasted resources and potential health risks

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They are exploring how it interacts with blood vessel growth, connective tissue, the digestive system, and wound healing
