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Description
The relative importance of the glutathione system compared to the more important thioredoxin system may be further amplified under acute oxidative challenge as thioredoxins or thioredoxin reductases may readily become limiting and/or oxidised and thus inactive 71 , which would strongly limit the capacity of the thioredoxin pathway to act as a conduit of antioxidative electron flux
A large number of unmetabolized APAP is metabolized by CYP2E1, resulting in excessive toxic intermediate NAPQI (Torres et al., 2019)
Tubulointerstitial damage is recognized as one of the pathological features of the lupus kidney, and tubulointerstitial inflammation is important in the assessment and prognosis of LN (68, 69)
Retrieved December 5, 2022
Liang W, Li Q, Ferrara N
PMID: 12 SunY-YZhuH-JZhaoR-YZhouS-YWangM-QYangYet al
