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Thiomethyl metabolites allow monitoring the elimination of the toxic fraction after acute intoxication We then monitored the presence of S-CH 3 -APAP-S and SO-CH 3 -APAP-S in blood samples collected from individuals who were admitted to hospital for suspicion of acute APAP intoxication (n=13, 11 women and 2 men)

doi: 10.4194/TRJFAS19802 25 FaisalM.HussainS

Unlike the other enzymes discussed in this review, no metabolic deficiencies have been identified with PDK as the root cause

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