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Mechanistically, hyperoside inhibits cyclin-dependent kinase 6, thereby promoting dephosphorylation and nuclear translocation of transcription factor EB, which in turn upregulates PGC-1 and uncoupling protein 1 to activate thermogenic programs in adipose tissue

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This ALCAR regime was based on previous work showing behavioural improvements after treatment with ALCAR (Schaevitz et al, 2012