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Metabolism of Melatonin by Cytochrome P-450s in Rat Liver Mitochondria and Microsomes

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2.6.1 Terpenoids 2.6.1.1 -Elemene As mentioned above, -Elemene can significantly inhibit PI3K/AKT/mTOR, MAPK pathways to induce apoptosis and autophagy, and combination of it with autophagy inhibitors can significantly enhance its anti-tumor effect (Liu et al., 2012b

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10.1054/bjoc.2001.1810 143 SedoA.VlasicovK.BartkP.VespalecR.VicarJ.SimnekV.et al (2002)

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L-Cysteine Amino acid that helps build glutathione, supports inflammation balance, and promotes natural energy

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Relatively smaller amounts of melatonin are produced in the retina compared with the pineal gland [96]

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