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In the United States, the prevalence of obesity among adults was 40.3 percent between 2021 and 2023 (213)Emmerich SD, et al

Determination of steady state parameters for all the compounds was not possible due to low solubility at high micromolar concentrations

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Cell viability detection with Annexin V/PI by flow cytometry ARPE-19 cells were rinsed with PBS

These findings were corroborated by overexpression of plasma membrane nutrient transporters, such as the glucose transporters (GLUTs) and some amino acid transporters such as ASCT2, LAT1, and ATB 0,+ , which became promising targets for pharmacological intervention

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