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The forward locomotion was tracked using the rats center mass of the hind-limbs method and plotted as total distance traveled (cm) for 240 minutes

[DOI] [PMC free article] [PubMed] [Google Scholar] Di Marco E, Gray SP, Kennedy K, Szyndralewiez C, Lyle AN, Lassgue B, Griendling KK, Cooper ME, Schmidt HHHW, Jandeleit-Dahm KAM

Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

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These observations for TGFBI and TTR suggest that lower circulating levels of these islet-associated proteins could reflect changes in beta cell function accompanying type 1 diabetes