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Drug Policy 26 (1), 2029
In hepatocyte mitochondria, the reaction of NH 3 with ATP and the bicarbonate ion (HCO 3 ) leads to the formation of carbamoyl phosphate (CP) by CP synthetase (CPS), a key intermediate in the urea cycle

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The orbitrap parameters were a noise threshold of 5 10 3 for MS1 and 2.5 10 3 for MS2, a minimum feature height of 5 10 4 , and m/z tolerances of 10 ppm (scan-to-scan), 5 ppm (intra-sample), and 5 ppm (inter-sample)

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