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Int J Antimicrob Agents
Despite beneficial effects mentioned above, a thorough understanding on the application of vitamin and antioxidant supplements such as effective dosage and administration method is necessary to avoid undesirable effects
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In particularly, ACSL4 plays a crucial role in regulating ferroptosis, and its overexpression boosts the synthesis of -pufa6 PUFA and encourages ferroptosis (51)
doi: 10.1016/j.freeradbiomed.2005.10.035 [DOI] [PubMed] [Google Scholar] [306].Matthews RT, Yang L, Jenkins BG, et al
The proliferation of cancer cells highly depends on the extracellular glutamine supply, termed glutamine addiction (Wise and Thompson, 2010)
