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In addition, high levels of HO-1 have been observed in various human solid tumors, such as renal [87], prostatic [88], and pancreatic cancers [89]
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The enzyme beta-secretase cleaves APP to produce A peptides, particularly A42, which aggregate into toxic oligomers that form plaques
demonstrated that IGF-1 overexpression in differentiated L6E9 cells resulted in pronounced myotube hypertrophy and myogenin induction [120]
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