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Malonyl-CoA also plays a vital role in PUFA synthesis, where dietary linoleic acid undergoes sequential desaturation and elongation reactions catalyzed by fatty acid desaturase (FADS)2, ELOVL5 and FADS1, leading to the formation of AA (C20:4, -6), which can be further elongated by ELOVL2/4 to generate AdA (C22:4, -6) (76)

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doi: 10.1016/j.ejphar.2023.175568 88 ChadhaSBehlTKumarAKhullarGAroraS

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It can activate the phosphoinositide 3-kinase/Akt (PI3K/Akt) signaling pathway, enhancing cell survival signals and contributing to the resilience of neurons under stress (76)

Some capsules are even made to absorb better in the gut of research animals