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The terminals of the villi have elevated expression of proteins involved in fatty acid metabolism and transporters, with analogous zonation observed in mesenchymal cells
However, substantial translational challenges remain, including variability in cell source and potency, limited persistence in joint environment, small clinical trial sizes, and regulatory and manufacturing hurdles

In particular, aerosol- or nebulizer-dosed NE inhibitors significantly improved their efficacy and lowered adverse effects (Mohamed et al., 2020)

T163775A138283056 (International Union for Conservation of Nature, 2020)

Ion channels as therapeutic antibody targets
