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Additional analytical methods, including X-ray based techniques 4,5 , laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) 6,7,8 , nano secondary ion mass spectrometry (nanoSIMS) 9 , and matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) 10 , have also been employed to image the distribution of metallodrugs in biological tissues

Nat Methods (2017) 14(4):4179

Acknowledgements This work was supported by the Global Nutrition Healthcare Council, Mission COVID (www.missioncovid.com)

The measurement of TAC represents a comprehensive evaluation methodology that quantifies the collective ability of biological systems to neutralize oxidative damage, offering valuable understanding of redox dysregulation and guiding therapeutic interventions focused on enhancing cellular protective mechanisms (Cao and Prior, 1999)