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The earliest sign of response is reduced shedding at 4 to 8 weeks, but visible new growth requires 8 to 16 weeks and meaningful density change takes 4 to 6 months

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The Challenge of Tendon and Ligament Healing Tendons and ligaments have notoriously poor blood supply, which is why these injuries often become chronic

116:109741 Thymosin beta-4 and peptide-mediated cellular signaling pathways Dou Y, Lee A, Zhu L, Morton J, Ladiges W., Aging Pathobiology and Therapeutics , 2020

Different bottleneck priorities and ratios