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Development and characterization of PLC knockout mice models revealed an important physiological role of this protein in the maintaining of cardiac and pancreatic functions by regulation of Ca 2+ mobilization in cells and cardiomyocytes [17-19]

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Dosing frequency in research protocols is typically daily or every 48 hours, depending on whether the goal is sustained receptor activation or pulsatile signaling

This could have resulted in a lower risk for complications including the development of a proliferative vitreoretinopathy and exudative retinal detachment thereby preserving the vision

administration, approximately 76% of the levocarnitine dose was excreted in urine during the 0 to 24h interval