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Data availability The cryo-EM maps of Apo MRP2, inward-facing and outward-facing MRP2(E1462Q), and LTC4-bound MRP2 have been deposited in the Electron Microscopy Data Bank under the accession codes EMD-45159, EMD-44833, EMD-44911, and EMD-45099, respectively

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For instance, electrical stimulation at specific acupoints significantly improves cognitive function and alleviates comorbid affective disorders (e.g

L-Glutathione is sulfurcontaining tripeptide composed of Glycine, Glutamic acid and Cysteine

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