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A model-based exposure-response (E-R) assessment of a nivolumab (NIVO) 4-weekly (Q4W) dosing schedule across multiple tumor types

This protective action highlights the importance of membrane-incorporated lipid peroxides as executors of ferroptosis

NIV may be used as a comfort measure for patients by minimizing adverse effects

[15] [16] Standard NHS treatment protocols: Without neurological involvement: Hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, then maintenance injections every 2-3 months (lifelong if pernicious anaemia)