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We have shown that effective pharmacologic inhibition of GPX4 in PTC cells with direct inhibitor RSL3 induces a robust activation of ferroptosis, increased DNA damage, impaired DNA damage repair response due to reduced p-NPM1 levels, decreased cell viability and cell migration, as well as suppressed spheroid formation and viability in vitro

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Quadrupling efficiency in production of genetically modified pigs through improved oocyte maturation

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For continuous Esm1 + cell tracking, pregnant females were injected with 2.5 mg tamoxifen (Sigma, #T5648) and progesterone (Sigma, #P3972) mixed in oil s.c
